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BMCBI
2005
151views more  BMCBI 2005»
13 years 7 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang
BMCBI
2005
116views more  BMCBI 2005»
13 years 7 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Correlation and prediction of gene expression level from amino acid and dipeptide composition of its protein
Background: A large number of papers have been published on analysis of microarray data with particular emphasis on normalization of data, detection of differentially expressed ge...
Gajendra P. S. Raghava, Joon H. Han
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
JCB
2007
146views more  JCB 2007»
13 years 7 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
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