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104
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BMCBI
2008
15 years 3 months ago
2008
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
163
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BMCBI
2008
15 years 3 months ago
2008
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
121
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BMCBI
2008
15 years 3 months ago
2008
Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
133
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BMCBI
2008
15 years 3 months ago
2008
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
103
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BMCBI
2008
15 years 3 months ago
2008
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...