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BMCBI
2008
108views more  BMCBI 2008»
13 years 10 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2008
105views more  BMCBI 2008»
13 years 10 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BMCBI
2008
107views more  BMCBI 2008»
13 years 10 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...
BMCBI
2008
168views more  BMCBI 2008»
13 years 10 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
CGF
2010
189views more  CGF 2010»
13 years 10 months ago
Space-in-Time and Time-in-Space Self-Organizing Maps for Exploring Spatiotemporal Patterns
Spatiotemporal data pose serious challenges to analysts in geographic and other domains. Owing to the complexity of the geospatial and temporal components, this kind of data canno...
Gennady L. Andrienko, Natalia V. Andrienko, Sebast...
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