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BIOINFORMATICS
2010
116views more  BIOINFORMATICS 2010»
13 years 7 months ago
A principal skeleton algorithm for standardizing confocal images of fruit fly nervous systems
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
Lei Qu, Hanchuan Peng
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
13 years 7 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
BMCBI
2008
148views more  BMCBI 2008»
13 years 7 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...