Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Background: Current imaging methods such as Magnetic Resonance Imaging (MRI), Confocal microscopy, Electron Microscopy (EM) or Selective Plane Illumination Microscopy (SPIM) yield...
Benjamin Schmid, Johannes E. Schindelin, Albert Ca...
The responses of cortical neurons are often characterized by measuring their spectro-temporal receptive fields (strfs). The strf of a cell can be thought of as a representation of...
Martin Coath, Emili Balaguer-Ballester, Sue L. Den...
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...