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BMCBI
2010
125views more  BMCBI 2010»
13 years 7 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2010
98views more  BMCBI 2010»
13 years 7 months ago
Prediction of protein structural classes for low-homology sequences based on predicted secondary structure
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
Jian-Yi Yang, Zhen-Ling Peng, Xin Chen
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
BMCBI
2008
72views more  BMCBI 2008»
13 years 7 months ago
HECTAR: A method to predict subcellular targeting in heterokonts
Background: The heterokonts are a particularly interesting group of eukaryotic organisms; they include many key species of planktonic and coastal algae and several important patho...
Bernhard Gschloessl, Yann Guermeur, J. Mark Cock
BMCBI
2010
243views more  BMCBI 2010»
13 years 7 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...