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» On consensus biomarker selection
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BMCBI
2008
129views more  BMCBI 2008»
13 years 6 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2004
97views more  BMCBI 2004»
13 years 6 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
TCBB
2010
108views more  TCBB 2010»
13 years 1 months ago
Identification of Full and Partial Class Relevant Genes
Multiclass cancer classification on microarray data has provided the feasibility of cancer diagnosis across all of the common malignancies in parallel. Using multiclass cancer feat...
Zexuan Zhu, Yew-Soon Ong, Jacek M. Zurada
STOC
2000
ACM
156views Algorithms» more  STOC 2000»
13 years 11 months ago
Near optimal multiple alignment within a band in polynomial time
Multiple sequence alignment is a fundamental problem in computational biology. Because of its notorious difficulties, aligning sequences within a constant band (c-diagonal) is a ...
Ming Li, Bin Ma, Lusheng Wang
BMCBI
2008
144views more  BMCBI 2008»
13 years 6 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath