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BMCBI
2010
102views more  BMCBI 2010»
13 years 8 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2008
141views more  BMCBI 2008»
13 years 8 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
BMCBI
2008
163views more  BMCBI 2008»
13 years 8 months ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
BMCBI
2008
150views more  BMCBI 2008»
13 years 8 months ago
Natural Language Processing in aid of FlyBase curators
Background: Despite increasing interest in applying Natural Language Processing (NLP) to biomedical text, whether this technology can facilitate tasks such as database curation re...
Nikiforos Karamanis, Ruth Seal, Ian Lewin, Peter M...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...