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BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
Predicting population coverage of T-cell epitope-based diagnostics and vaccines
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
Huynh-Hoa Bui, John Sidney, Kenny Dinh, Scott Sout...
BMCBI
2006
169views more  BMCBI 2006»
13 years 8 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
BMCBI
2006
126views more  BMCBI 2006»
13 years 8 months ago
Effect of data normalization on fuzzy clustering of DNA microarray data
Background: Microarray technology has made it possible to simultaneously measure the expression levels of large numbers of genes in a short time. Gene expression data is informati...
Seo Young Kim, Jae Won Lee, Jong Sung Bae
BMCBI
2006
90views more  BMCBI 2006»
13 years 8 months ago
The PowerAtlas: a power and sample size atlas for microarray experimental design and research
Background: Microarrays permit biologists to simultaneously measure the mRNA abundance of thousands of genes. An important issue facing investigators planning microarray experimen...
Grier P. Page, Jode W. Edwards, Gary L. Gadbury, P...
BMCBI
2006
74views more  BMCBI 2006»
13 years 8 months ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
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