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JCB
2006
125views more  JCB 2006»
13 years 7 months ago
Hypothesis Generation in Signaling Networks
Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulati...
Derek A. Ruths, Luay Nakhleh, M. Sriram Iyengar, S...
NAR
2008
191views more  NAR 2008»
13 years 7 months ago
The BioGRID Interaction Database: 2008 update
The Biological General Repository for Interaction Datasets (BioGRID) database (http://www. thebiogrid.org) was developed to house and distribute collections of protein and genetic...
Bobby-Joe Breitkreutz, Chris Stark, Teresa Reguly,...
BMCBI
2005
142views more  BMCBI 2005»
13 years 7 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
BMCBI
2004
131views more  BMCBI 2004»
13 years 7 months ago
A web services choreography scenario for interoperating bioinformatics applications
Background: Very often genome-wide data analysis requires the interoperation of multiple databases and analytic tools. A large number of genome databases and bioinformatics applic...
Remko de Knikker, Youjun Guo, Jin-long Li, Albert ...