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» On genomic coding theory
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BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen
BMCBI
2010
148views more  BMCBI 2010»
13 years 7 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2006
74views more  BMCBI 2006»
13 years 7 months ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
CF
2007
ACM
13 years 11 months ago
Parallel genomic sequence-search on a massively parallel system
In the life sciences, genomic databases for sequence search have been growing exponentially in size. As a result, faster sequencesearch algorithms to search these databases contin...
Oystein Thorsen, Brian E. Smith, Carlos P. Sosa, K...
NAR
2002
164views more  NAR 2002»
13 years 7 months ago
SCOP database in 2002: refinements accommodate structural genomics
The SCOP (Structural Classification of Proteins) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Loredana Lo Conte, Steven E. Brenner, Tim J. P. Hu...