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SIGMOD
2008
ACM
140views Database» more  SIGMOD 2008»
14 years 7 months ago
Skippy: a new snapshot indexing method for time travel in the storage manager
The storage manager of a general-purpose database system can retain consistent disk page level snapshots and run application programs "back-in-time" against long-lived p...
Ross Shaull, Liuba Shrira, Hao Xu
TFS
2010
152views Education» more  TFS 2010»
13 years 2 months ago
Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T-S Fuzzy Approach
At present, the development in the nascent field of synthetic gene networks is still difficult. Most newly created gene networks are nonfunctioning due to intrinsic parameter fluct...
Bor-Sen Chen, Chih-Hung Wu
EVOW
2004
Springer
14 years 29 days ago
Iteratively Inferring Gene Regulatory Networks with Virtual Knockout Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We introduce enhancements to an Evolutionary Algorithm op...
Christian Spieth, Felix Streichert, Nora Speer, An...
BMCBI
2006
194views more  BMCBI 2006»
13 years 7 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Inverse Design of Large Molecules using Linear Diophantine Equations
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...
Shawn Martin, W. Michael Brown, Jean-Loup Faulon, ...