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» On the Associative Nijenhuis Relation
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BMCBI
2010
162views more  BMCBI 2010»
13 years 8 months ago
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Che...
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...
BMCBI
2010
115views more  BMCBI 2010»
13 years 8 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BMCBI
2010
130views more  BMCBI 2010»
13 years 8 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BMCBI
2010
107views more  BMCBI 2010»
13 years 8 months ago
Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network
Background: Pathways in biological system often cooperate with each other to function. Changes of interactions among pathways tightly associate with alterations in the properties ...
Yezhou Huang, Shao Li