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» On the Autoreducibility of Random Sequences
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NAACL
2003
13 years 9 months ago
Implicit Trajectory Modeling through Gaussian Transition Models for Speech Recognition
It is well known that frame independence assumption is a fundamental limitation of current HMM based speech recognition systems. By treating each speech frame independently, HMMs ...
Hua Yu, Tanja Schultz
ISMB
1996
13 years 9 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
DAC
2007
ACM
14 years 8 months ago
Synthesizing Stochasticity in Biochemical Systems
Randomness is inherent to biochemistry: at each instant, the sequence of reactions that fires is a matter of chance. Some biological systems exploit such randomness, choosing betw...
Brian Fett, Jehoshua Bruck, Marc D. Riedel