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BMCBI
2010
138views more  BMCBI 2010»
15 years 6 months ago
UFFizi: a generic platform for ranking informative features
Background: Feature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or cluste...
Assaf Gottlieb, Roy Varshavsky, Michal Linial, Dav...
BMCBI
2010
132views more  BMCBI 2010»
15 years 6 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2010
165views more  BMCBI 2010»
15 years 6 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2010
86views more  BMCBI 2010»
15 years 6 months ago
Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
Qian Liu, Jinyan Li
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