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BMCBI
2010
130views more  BMCBI 2010»
15 years 6 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2007
100views more  BMCBI 2007»
15 years 6 months ago
SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)
Background: The need to build a tool to facilitate the quick creation and editing of models encoded in the Systems Biology Markup language (SBML) has been growing with the number ...
Nicolas Rodriguez, Marco Donizelli, Nicolas Le Nov...
BMCBI
2010
132views more  BMCBI 2010»
15 years 6 months ago
Next generation tools for genomic data generation, distribution, and visualization
Background: With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the ...
David A. Nix, Tonya L. Di Sera, Brian K. Dalley, B...
BMCBI
2010
149views more  BMCBI 2010»
15 years 6 months ago
A multifactorial analysis of obesity as CVD risk factor: Use of neural network based methods in a nutrigenetics context
Background: Obesity is a multifactorial trait, which comprises an independent risk factor for cardiovascular disease (CVD). The aim of the current work is to study the complex eti...
Ioannis K. Valavanis, Stavroula G. Mougiakakou, Ke...
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