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144
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BMCBI
2006
15 years 5 months ago
2006
Background: Knowledge of the subcellular location of a protein is critical to understanding how that protein works in a cell. This location is frequently determined by the interpr...
164
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BMCBI
2006
15 years 5 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
177
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BMCBI
2006
15 years 5 months ago
2006
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
154
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BMCBI
2006
15 years 5 months ago
2006
Background: Two-dimensional data colourings are an effective medium by which to represent three-dimensional data in two dimensions. Such "color-grid" representations hav...
177
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BMCBI
2006
15 years 5 months ago
2006
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...