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BMCBI
2005
94views more  BMCBI 2005»
13 years 9 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
BMCBI
2005
115views more  BMCBI 2005»
13 years 9 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
BMCBI
2005
169views more  BMCBI 2005»
13 years 9 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
100views more  BMCBI 2005»
13 years 9 months ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich
BMCBI
2005
147views more  BMCBI 2005»
13 years 9 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
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