Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
Software can be considered a live entity, as it undergoes many alterations throughout its lifecycle. Furthermore, developers do not usually retain a good design in favor of adding...
Marios Fokaefs, Nikolaos Tsantalis, Alexander Chat...
Let G = (V, E, w) be a directed graph, where w : V → R is an arbitrary weight function defined on its vertices. The bottleneck weight, or the capacity, of a path is the smalles...
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
To understand the functional connectivity of neural networks, it is important to develop simple and incisive descriptors of multineuronal firing patterns. Analysis at the pairwise...