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BMCBI
2008
13 years 9 months ago
2008
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
BMCBI
2008
13 years 9 months ago
2008
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
BMCBI
2008
13 years 9 months ago
2008
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
BMCBI
2008
13 years 9 months ago
2008
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
BMCBI
2008
13 years 9 months ago
2008
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...