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BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
BMCBI
2006
131views more  BMCBI 2006»
13 years 8 months ago
SIMAGE: simulation of DNA-microarray gene expression data
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
Casper J. Albers, Ritsert C. Jansen, Jan Kok, Osca...
ICML
2001
IEEE
14 years 9 months ago
Feature selection for high-dimensional genomic microarray data
We report on the successful application of feature selection methods to a classification problem in molecular biology involving only 72 data points in a 7130 dimensional space. Ou...
Eric P. Xing, Michael I. Jordan, Richard M. Karp
BMCBI
2005
163views more  BMCBI 2005»
13 years 8 months ago
Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
Nitin Jain, HyungJun Cho, Michael O'Connell, Jae K...
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 2 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...