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» On the Evaluation of Entity Profiles
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BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...
BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
Indirect two-sided relative ranking: a robust similarity measure for gene expression data
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
Louis Licamele, Lise Getoor
BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
BMCBI
2010
93views more  BMCBI 2010»
13 years 7 months ago
HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data
Background: Tiling-arrays are applicable to multiple types of biological research questions. Due to its advantages (high sensitivity, resolution, unbiased), the technology is ofte...
Erdogan Taskesen, Renee Beekman, Jeroen de Ridder,...
BMCBI
2010
89views more  BMCBI 2010»
13 years 7 months ago
Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)
Background: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentratio...
Jennifer M. Staab, Thomas M. O'Connell, Shawn M. G...