Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
One of the aims of modern Bioinformatics is to discover the molecular mechanisms that rule the protein operation. This would allow us to understand the complex processes involved i...
A number of medically important disease-causing bacteria (collectively called Gram-negative bacteria) are noted for the extra "outer" membrane that surrounds their cell....
Rong She, Fei Chen 0002, Ke Wang, Martin Ester, Je...
Abstract. The protein family classification problem, which consists of determining the family memberships of given unknown protein sequences, is very important for a biologist for ...