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BMCBI
2006
119views more  BMCBI 2006»
13 years 7 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
Discrete profile comparison using information bottleneck
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
Automatic document classification of biological literature
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...
David Chen, Hans-Michael Müller, Paul W. Ster...
CLASSIFICATION
2006
108views more  CLASSIFICATION 2006»
13 years 7 months ago
The Practice of Cluster Analysis
Abstracts "Mixtures at the Interface" David Scott, Rice University Mixture modeling provides an effective framework for complex, high-dimensional data. The potential of m...
Jon R. Kettenring