A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Some initial results on the study of conformon-P systems with negative values are reported. One model of these conformon-P systems is proved to be computationally universal while a...
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...
Weconsider tile automatedidentification of transmembrane domains in membrane protein sequences. 324 proteins (containing 1585 segrrmnts) werc examined, representing every protein ...