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» On the Power of Computing with Proteins on Membranes
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ISMB
1998
14 years 7 days ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
14 years 4 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu
MEMBRANE
2007
Springer
14 years 5 months ago
Conformon-P Systems with Negative Values
Some initial results on the study of conformon-P systems with negative values are reported. One model of these conformon-P systems is proved to be computationally universal while a...
Pierluigi Frisco
BMCBI
2008
98views more  BMCBI 2008»
13 years 11 months ago
PredGPI: a GPI-anchor predictor
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...
ISMB
1993
14 years 6 days ago
Transmembrane Segment Prediction from Protein Sequence Data
Weconsider tile automatedidentification of transmembrane domains in membrane protein sequences. 324 proteins (containing 1585 segrrmnts) werc examined, representing every protein ...
Sholom M. Weiss, Dawn M. Cohen, Nitin Indurkhya