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» On the Satisfiability of Complex Constraints
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IJCAI
1993
15 years 7 months ago
Provably Bounded Optimal Agents
Since its inception, arti cial intelligence has relied upon a theoretical foundation centred around perfect rationality as the desired property of intelligent systems. We argue, a...
Stuart J. Russell, Devika Subramanian, Ronald Parr
CEC
2010
IEEE
15 years 7 months ago
Constrained global optimization of low-thrust interplanetary trajectories
The optimization of spacecraft trajectories can be formulated as a global optimization task. The complexity of the problem depends greatly on the problem formulation, on the spacec...
Chit Hong Yam, David Di Lorenzo, Dario Izzo
BMCBI
2010
84views more  BMCBI 2010»
15 years 6 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
178views more  BMCBI 2008»
15 years 6 months ago
Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...