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BIBM
2007
IEEE
133views Bioinformatics» more  BIBM 2007»
13 years 10 months ago
Mining Clinical Data with a Temporal Dimension: A Case Study
Clinical databases store large amounts of information about patients and their medical conditions. Data mining techniques can extract relationships and patterns holding in this we...
Michele Berlingerio, Francesco Bonchi, Fosca Giann...
AI
2010
Springer
13 years 10 months ago
Optimal query complexity bounds for finding graphs
We consider the problem of finding an unknown graph by using two types of queries with an additive property. Given a graph, an additive query asks the number of edges in a set of ...
Sung-Soon Choi, Jeong Han Kim
BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
156views more  BMCBI 2010»
13 years 10 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BMCBI
2008
92views more  BMCBI 2008»
13 years 10 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
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