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BMCBI
2010
112views more  BMCBI 2010»
13 years 9 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2010
153views more  BMCBI 2010»
13 years 9 months ago
VITCOMIC: visualization tool for taxonomic compositions of microbial communities based on 16S rRNA gene sequences
Background: Understanding the community structure of microbes is typically accomplished by sequencing 16S ribosomal RNA (16S rRNA) genes. These community data can be represented b...
Hiroshi Mori, Fumito Maruyama, Ken Kurokawa
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
CORR
2010
Springer
249views Education» more  CORR 2010»
13 years 9 months ago
Lower Bounds on Near Neighbor Search via Metric Expansion
In this paper we show how the complexity of performing nearest neighbor (NNS) search on a metric space is related to the expansion of the metric space. Given a metric space we loo...
Rina Panigrahy, Kunal Talwar, Udi Wieder