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BMCBI
2006
74views more  BMCBI 2006»
13 years 9 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
BMCBI
2005
127views more  BMCBI 2005»
13 years 9 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2010
141views more  BMCBI 2010»
13 years 10 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
NN
2006
Springer
141views Neural Networks» more  NN 2006»
13 years 9 months ago
Encoding uncertainty in the hippocampus
The medial temporal lobe may play a critical role in binding successive events into memory while encoding contextual information in implicit and explicit memory tasks. Information...
Lee M. Harrison, Andrew Duggins, Karl J. Friston
JCB
2000
146views more  JCB 2000»
13 years 9 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag