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» On the decomposition of rational functions
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BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
SODa: An Mn/Fe superoxide dismutase prediction and design server
Background: Superoxide dismutases (SODs) are ubiquitous metalloenzymes that play an important role in the defense of aerobic organisms against oxidative stress, by converting reac...
Jean Marc Kwasigroch, René Wintjens, Dimitr...
BMCBI
2008
128views more  BMCBI 2008»
13 years 8 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2008
244views more  BMCBI 2008»
13 years 8 months ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
BMCBI
2008
152views more  BMCBI 2008»
13 years 8 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...