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BMCBI
2010
142views more  BMCBI 2010»
13 years 6 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
BMCBI
2010
121views more  BMCBI 2010»
13 years 6 months ago
A grammar-based distance metric enables fast and accurate clustering of large sets of 16S sequences
Background: We propose a sequence clustering algorithm and compare the partition quality and execution time of the proposed algorithm with those of a popular existing algorithm. T...
David J. Russell, Samuel F. Way, Andrew K. Benson,...
BMCBI
2010
162views more  BMCBI 2010»
13 years 6 months ago
SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels
Background: Expression levels for 47294 transcripts in lymphoblastoid cell lines from all 270 HapMap phase II individuals, and genotypes (both HapMap phase II and III) of 3.96 mil...
Kristian Holm, Espen Melum, Andre Franke, Tom H. K...
BMCBI
2010
108views more  BMCBI 2010»
13 years 6 months ago
Prediction of RNA secondary structure by maximizing pseudo-expected accuracy
Background: Recent studies have revealed the importance of considering the entire distribution of possible secondary structures in RNA secondary structure predictions; therefore, ...
Michiaki Hamada, Kengo Sato, Kiyoshi Asai
BMCBI
2010
161views more  BMCBI 2010»
13 years 6 months ago
Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers
Background: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of ...
Mohammed Dakna, Keith Harris, Alexandros Kalousis,...
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