6652 search results - page 1274 / 1331 » On the effective evaluation of TCP |
BMCBI
2010
13 years 7 months ago
2010
Background: Previous studies on insect DNA barcoding provide contradictory results and suggest not consistent performances across orders. This work aims at providing a general eva...
BMCBI
2010
13 years 7 months ago
2010
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
BMCBI
2010
13 years 7 months ago
2010
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
BMCBI
2010
13 years 7 months ago
2010
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
BMCBI
2010
13 years 7 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...