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BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
Genomes as geography: using GIS technology to build interactive genome feature maps
Background: Many commonly used genome browsers display sequence annotations and related attributes as horizontal data tracks that can be toggled on and off according to user prefe...
Mary E. Dolan, Constance C. Holden, M. Kate Beard,...
BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
CORR
2006
Springer
81views Education» more  CORR 2006»
13 years 7 months ago
The Workshop on Internet Topology (WIT) Report
Internet topology analysis has recently experienced a surge of interest in computer science, physics, and the mathematical sciences. However, researchers from these different disc...
Dmitri V. Krioukov, Fan R. K. Chung, Kimberly C. C...
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