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154
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BMCBI
2010
15 years 4 months ago
2010
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
125
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BMCBI
2010
15 years 4 months ago
2010
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
149
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BMCBI
2010
15 years 4 months ago
2010
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
151
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BMCBI
2010
15 years 4 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
140
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BMCBI
2010
15 years 4 months ago
2010
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...