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130
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BMCBI
2010
15 years 4 months ago
2010
Background: With the continuously increasing demands on knowledge- and data-management that databases have to meet, ontologies and the theories of granularity they use become more...
151
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BMCBI
2010
15 years 4 months ago
2010
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
150
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BMCBI
2010
15 years 4 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
135
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BMCBI
2010
15 years 4 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
132
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BMCBI
2010
15 years 4 months ago
2010
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...