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FUIN
2008
119views more  FUIN 2008»
15 years 4 months ago
Modeling Communication with Synchronized Environments
A deterministic behavior of systems composed of several modules is a desirable design goal. Assembling a complex system from components requires also a high degree of re-usability....
Tiberiu Seceleanu, Axel Jantsch
BMCBI
2006
159views more  BMCBI 2006»
15 years 4 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
BMCBI
2006
152views more  BMCBI 2006»
15 years 4 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2006
122views more  BMCBI 2006»
15 years 4 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2006
88views more  BMCBI 2006»
15 years 4 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
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