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» On theoretical backgrounds of CAD
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BMCBI
2005
67views more  BMCBI 2005»
13 years 7 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao
BMCBI
2005
163views more  BMCBI 2005»
13 years 7 months ago
Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
Nitin Jain, HyungJun Cho, Michael O'Connell, Jae K...
BMCBI
2005
84views more  BMCBI 2005»
13 years 7 months ago
A note on generalized Genome Scan Meta-Analysis statistics
Background: Wise et al. introduced a rank-based statistical technique for meta-analysis of genome scans, the Genome Scan Meta-Analysis (GSMA) method. Levinson et al. recently desc...
James A. Koziol, Anne C. Feng
BMCBI
2005
106views more  BMCBI 2005»
13 years 7 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...