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BMCBI
2004
106views more  BMCBI 2004»
13 years 8 months ago
ESTIMA, a tool for EST management in a multi-project environment
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
BMCBI
2004
177views more  BMCBI 2004»
13 years 8 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2004
173views more  BMCBI 2004»
13 years 8 months ago
d-matrix - database exploration, visualization and analysis
Background: Motivated by a biomedical database set up by our group, we aimed to develop a generic database front-end with embedded knowledge discovery and analysis features. A maj...
Dominik Seelow, Raffaello Galli, Siegrun Mebus, Ha...
BMCBI
2004
146views more  BMCBI 2004»
13 years 8 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
CORR
2004
Springer
133views Education» more  CORR 2004»
13 years 8 months ago
Information theory, multivariate dependence, and genetic network inference
We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of in...
Ilya Nemenman
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