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BMCBI
2010
136views more  BMCBI 2010»
15 years 4 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
149
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BMCBI
2010
124views more  BMCBI 2010»
15 years 4 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
141
Voted
BMCBI
2010
155views more  BMCBI 2010»
15 years 4 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2008
202views more  BMCBI 2008»
15 years 4 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
146views more  BMCBI 2008»
15 years 4 months ago
A phase synchronization clustering algorithm for identifying interesting groups of genes from cell cycle expression data
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
Chang Sik Kim, Cheol Soo Bae, Hong Joon Tcha