Semantic similarity measures have been used successfully and extensively in the biomedical research with various applications. As the biomedical ontologies, which form the main gro...
: We propose an approach for quantifying the biological relatedness between gene products, based on their properties, and measure their similarities using exclusively statistical N...
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
The use of controlled structured vocabularies for annotation purposes, such as the Gene Ontology (GO) is currently one of the strategies to cope with the increasingly cumbersome t...
There is a need to develop methods to automatically incorporate prior knowledge to support the prediction and validation of novel functional associations. One such important sourc...
Francisco Azuaje, Haiying Wang, Huiru Zheng, Olivi...