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BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
Romesh Stanislaus, Mark Carey, Helena F. Deus, Kev...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
Exploration and visualization of gene expression with neuroanatomy in the adult mouse brain
Background: Spatially mapped large scale gene expression databases enable quantitative comparison of data measurements across genes, anatomy, and phenotype. In most ongoing effort...
Christopher Lau, Lydia Ng, Carol Thompson, Sayan D...
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...