11561 search results - page 2271 / 2313 » Open Distributed Processing |
BMCBI
2010
13 years 9 months ago
2010
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
BMCBI
2008
13 years 9 months ago
2008
Background: The traditional (unweighted) k-means is one of the most popular clustering methods for analyzing gene expression data. However, it suffers three major shortcomings. It...
BMCBI
2010
13 years 9 months ago
2010
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
BMCBI
2008
13 years 9 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2010
13 years 9 months ago
2010
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...