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BMCBI
2010
101views more  BMCBI 2010»
13 years 7 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
BMCBI
2010
102views more  BMCBI 2010»
13 years 7 months ago
Missing genes in the annotation of prokaryotic genomes
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
BMCBI
2004
135views more  BMCBI 2004»
13 years 7 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
ISMB
2007
13 years 10 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral