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CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Inverse Design of Large Molecules using Linear Diophantine Equations
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...
Shawn Martin, W. Michael Brown, Jean-Loup Faulon, ...
SIGIR
2005
ACM
15 years 9 months ago
Linear discriminant model for information retrieval
This paper presents a new discriminative model for information retrieval (IR), referred to as linear discriminant model (LDM), which provides a flexible framework to incorporate a...
Jianfeng Gao, Haoliang Qi, Xinsong Xia, Jian-Yun N...
VLSID
1999
IEEE
87views VLSI» more  VLSID 1999»
15 years 8 months ago
Digital Circuit Design for Minimum Transient Energy and a Linear Programming Method
This paper provides a theoretical basis for eliminating or reducing the energy consumption due to transients in a synchronous digital circuit. The transient energy is minimized wh...
Vishwani D. Agrawal, Michael L. Bushnell, Ganapath...
SIAMSC
2008
179views more  SIAMSC 2008»
15 years 3 months ago
Multigrid Algorithms for Inverse Problems with Linear Parabolic PDE Constraints
Abstract. We present a multigrid algorithm for the solution of distributed parameter inverse problems constrained by variable-coefficient linear parabolic partial differential equa...
Santi S. Adavani, George Biros
TSP
2010
14 years 10 months ago
Distributed sparse linear regression
The Lasso is a popular technique for joint estimation and continuous variable selection, especially well-suited for sparse and possibly under-determined linear regression problems....
Gonzalo Mateos, Juan Andrés Bazerque, Georg...