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BMCBI
2006
112views more  BMCBI 2006»
13 years 9 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
BMCBI
2006
119views more  BMCBI 2006»
13 years 9 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2006
116views more  BMCBI 2006»
13 years 9 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2006
137views more  BMCBI 2006»
13 years 9 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
IVC
2008
147views more  IVC 2008»
13 years 9 months ago
Distinctive and compact features
We consider the problem of extracting features for multi-class recognition problems. The features are required to make fine distinction between similar classes, combined with tole...
Ayelet Akselrod-Ballin, Shimon Ullman