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BMCBI
2008
155views more  BMCBI 2008»
13 years 7 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Simple and flexible classification of gene expression microarrays via Swirls and Ripples
Background: A simple classification rule with few genes and parameters is desirable when applying a classification rule to new data. One popular simple classification rule, diagon...
Stuart G. Baker
BMCBI
2008
118views more  BMCBI 2008»
13 years 7 months ago
Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
Rekin's Janky, Jacques van Helden
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...
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