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» Optimal detection of sequence similarity by local alignment
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IPPS
2006
IEEE
14 years 1 months ago
Parallel multiple sequence alignment with local phylogeny search by simulated annealing
The problem of multiple sequence alignment is one of the most important problems in computational biology. In this paper we present a new method that simultaneously performs multi...
Jaroslaw Zola, Denis Trystram, Andrei Tchernykh, C...
BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
GECCO
2003
Springer
128views Optimization» more  GECCO 2003»
14 years 26 days ago
Evolving Consensus Sequence for Multiple Sequence Alignment with a Genetic Algorithm
In this paper we present an approach that evolves the consensus sequence [25] for multiple sequence alignment (MSA) with genetic algorithm (GA). We have developed an encoding schem...
Conrad Shyu, James A. Foster
ICIC
2009
Springer
14 years 2 months ago
A Method for Multiple Sequence Alignment Based on Particle Swarm Optimization
Sequence Alignment is a basic information disposal method in Bioinformatics. However, it is difficult to deal with multiple sequence alignment problem(MSA). In this paper, an impro...
Fasheng Xu, Yuehui Chen