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BMCBI
2005
178views more  BMCBI 2005»
15 years 6 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
GECCO
2003
Springer
189views Optimization» more  GECCO 2003»
15 years 11 months ago
A Forest Representation for Evolutionary Algorithms Applied to Network Design
Abstract. Network design involves several areas of engineering and science. Computer networks, electrical circuits, transportation problems, and phylogenetic trees are some example...
Alexandre C. B. Delbem, André Carlos Ponce ...
BMCBI
2006
100views more  BMCBI 2006»
15 years 6 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...
BMCBI
2005
81views more  BMCBI 2005»
15 years 6 months ago
Evolutionary sequence analysis of complete eukaryote genomes
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
Jaime E. Blair, Prachi Shah, S. Blair Hedges