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» Optimal spliced alignments of short sequence reads
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AAAI
2000
13 years 10 months ago
Divide-and-Conquer Frontier Search Applied to Optimal Sequence Alignment
We present a new algorithm that reduces the space complexity of heuristic search. It is most effective for problem spaces that grow polynomially with problem size, but contain lar...
Richard E. Korf, Weixiong Zhang
BMCBI
2011
13 years 4 days ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
BMCBI
2010
142views more  BMCBI 2010»
13 years 8 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
IPPS
2009
IEEE
14 years 3 months ago
Accelerating error correction in high-throughput short-read DNA sequencing data with CUDA
Emerging DNA sequencing technologies open up exciting new opportunities for genome sequencing by generating read data with a massive throughput. However, produced reads are signif...
Haixiang Shi, Bertil Schmidt, Weiguo Liu, Wolfgang...
WABI
2009
Springer
132views Bioinformatics» more  WABI 2009»
14 years 3 months ago
mpscan: Fast Localisation of Multiple Reads in Genomes
Abstract. With Next Generation Sequencers, sequence based transcriptomic or epigenomic assays yield millions of short sequence reads that need to be mapped back on a reference geno...
Eric Rivals, Leena Salmela, Petteri Kiiskinen, Pet...