This paper gives a theoretical and empirical analysis of the time complexity of genetic algorithms (GAs) on problems with exponentially scaled building blocks. It is important to ...
Fernando G. Lobo, David E. Goldberg, Martin Pelika...
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
The Hierarchical Mixture of Experts (HME) is a well-known tree-structured model for regression and classification, based on soft probabilistic splits of the input space. In its o...
Abstract. A protein is a linear chain of amino acids that folds into a unique functional structure, called its native state. In this state, proteins show repeated substructures lik...
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...